Dry skin
Supporting the internal factors associated with dry skin — skin barrier function, hydration and connective tissue support.
The biological basis of dry skin — and how internal support fits alongside a skincare routine.
Dry skin (xerosis) is influenced by both surface events and internal biological function. While moisturisers act primarily at the skin’s surface, the skin’s ability to hold water and maintain a healthy barrier is governed by underlying biology — the integrity of the outer skin barrier, the lipids that limit water loss, and the connective tissue that supports skin structure.
Dermatology literature describes the skin barrier as the principal regulator of hydration, with barrier quality, lipid content and connective tissue all contributing to how well skin retains moisture. Internal factors — antioxidant defence, collagen and connective-tissue support, and micronutrient status relevant to barrier maintenance — together shape the internal environment in which the skin maintains hydration and structure.
The Dry Skin formulation is designed to support the internal cofactors these processes depend on — providing a consistent internal foundation that sits alongside a patient’s topical skincare routine, not in place of it.
What’s in the Dry skin formulation — and why
This formulation represents the standard base composition for dry skin, designed for general clinical use and practitioner-led recommendation.
Each active is included at a defined dose for its documented role in a pathway relevant to skin hydration and structure. Where direct dry-skin evidence is limited, this is reflected in the wording — a key advantage of pharmacist compounding over standardised manufactured supplements.
| Ingredient | Primary pathway relevance | Mechanism | Evidence summary | Key reference |
|---|---|---|---|---|
| Vitamin A1000 IU | Epithelial maintenance | Supports maintenance and differentiation of epithelial tissue | Supports normal epithelial function, maintenance and differentiation of skin tissue | NIH Office of Dietary Supplements. Vitamin A Fact Sheet. |
| Vitamin C300 mg | Collagen formation; antioxidant defence | Required for collagen synthesis and contributes to antioxidant protection | Reviews confirm vitamin C’s role in collagen synthesis and antioxidant defence in skin | Pullar JM et al. Nutrients. 2017;9(8):866 |
| Vitamin D3 (cholecalciferol)1000 IU | Epidermal & immune function | Participates in epidermal differentiation and immune regulation | Participates in epidermal differentiation and immune regulation; supports skin health where nutritional status is suboptimal | NIH Office of Dietary Supplements. Vitamin D Fact Sheet. |
| Vitamin E100 IU | Antioxidant defence | Lipid-soluble antioxidant protecting membrane lipids from oxidation | Lipid-phase antioxidant protecting membrane lipids from oxidative damage, with relevance to barrier resilience | Faghihi G et al. Journal of Research in Medical Sciences. 2015;20(11):1053–1057 |
| Zinc picolinate25 mg (elemental zinc ~5 mg) | Barrier repair; wound healing | Supports protein synthesis, immune function and normal wound healing | Zinc supports protein synthesis, immune function and normal wound healing; adequate status supports skin health | NIH Office of Dietary Supplements. Zinc Fact Sheet. |
| Silica150 mg | Connective tissue support | Bioavailable silicon supports collagen and connective tissue | An oral silicon randomised controlled trial reported improved skin surface and mechanical properties in photodamaged skin | Barel A et al. Archives of Dermatological Research. 2005;297(4):147–153 |
References describe the pathway and supporting evidence relevant to each ingredient. This formulation supports the biological processes associated with dry skin and is not intended to diagnose, treat, cure or prevent the condition.
Pharmaceutical-grade precision. Every ingredient has a purpose.
The Dry skin formulation is compounded by licensed Australian pharmacists within established TGA regulatory frameworks, using pharmaceutical-grade raw materials selected for documented roles in barrier support, antioxidant defence and connective tissue support.
The compounding approachTwo contexts, one formulation
The Dry Skin formulation is designed to support skin from within as part of a patient’s daily routine. For patients managing persistent dryness, it provides a consistent internal foundation targeting antioxidant defence, connective tissue support and the factors associated with barrier function and hydration.
Moisturisers and topical treatments act on the skin’s surface to reduce water loss. This formulation supports the internal resources — antioxidant defence, collagen and connective-tissue support and micronutrient status — that sit beneath those surface processes, complementing a patient’s skincare routine rather than replacing it.
Ready to order the Dry skin formulation for your clinic?
All formulations are compounded fresh to order and shipped directly to your clinic.