Balance
Supporting structural collagen integrity, barrier function and skin repair through the menopausal transition.
The skin biology of menopause — and how Balance addresses it.
The decline in oestrogen that characterises the menopausal transition has direct and measurable consequences for skin biology. Collagen synthesis slows markedly — with studies estimating a loss of approximately 30% of dermal collagen in the first five years following menopause. Concurrent reductions in hyaluronic acid and ceramide production compromise barrier function, while epidermal thinning increases transepidermal water loss and sensitivity.
These changes manifest progressively — as increased laxity, persistent dryness, slower wound healing, reduced tolerance to treatments and a general decline in skin resilience. They are driven by hormonal shifts but mediated by the availability of the structural proteins, antioxidants and micronutrients that skin depends on to maintain its architecture and repair capacity.
Balance is formulated to support the internal cofactors that these processes depend on — providing consistent nutritional support for collagen synthesis, epidermal renewal, barrier integrity and anti-inflammatory defence throughout the menopausal transition and beyond.
What’s in Balance — and why
This formulation represents the standard base composition, designed for general clinical use and practitioner-led recommendation.
All active ingredients are included at therapeutically relevant doses — calibrated to the levels demonstrated in published clinical evidence, and a key advantage of pharmacist compounding over standardised manufactured supplements.
| Ingredient | Primary pathway relevance | Mechanism | Evidence summary | Key reference |
|---|---|---|---|---|
| MSM300 mg | Skin structure; ageing; inflammation | Sulfur donor supporting collagen and keratin structural integrity with anti-inflammatory relevance to connective tissue and skin appearance | Randomised clinical evidence supports MSM for improving visible signs of skin ageing, including laxity and firmness | Muizzuddin N, Benjamin R. Nat Med J. 2020;15(3):4178520268698 |
| KSM-66 Ashwagandha200 mg | Menopausal symptoms; stress; indirect skin support | Adaptogenic support for stress, sleep and climacteric symptom burden, all of which can influence skin quality during the menopausal transition | Randomised controlled trials demonstrate improvement in climacteric symptoms in perimenopausal women, including the stress and sleep measures that influence skin quality through the menopausal transition | Gopal S et al. J Obstet Gynaecol. 2021;41(4):4446–4426 |
| Vitamin C50 mg | Collagen synthesis; antioxidant defence | Required for collagen hydroxylation and connective tissue formation | Strong biological and clinical support for vitamin C in collagen synthesis and antioxidant protection | Pullar JM et al. Nutrients. 2017;9(8):866 |
| Vitamin E20 mg | Barrier function; antioxidant defence | Lipid-phase antioxidant protecting cell membranes from oxidative stress | Evidence supports vitamin E as a lipid-phase antioxidant protecting cell membranes, with direct relevance to barrier function | Thiele U, Drangel–Musfarvadga S. Mol Aspects Med. 2007;28(5):461–467 |
| Vitamin A2500 IU | Cellular turnover; tissue maintenance | Regulates keratinocyte differentiation and epidermal renewal | Well-established biological and review evidence links adequate vitamin A status to normal epithelial integrity, turnover and maintenance | VanBuren E, Everts HB. Nutrients. 2022;14(14):2952 |
Pharmaceutical-grade precision. Every ingredient has a purpose.
Balance is compounded by licensed Australian pharmacists within established TGA regulatory frameworks, using pharmaceutical-grade raw materials selected for documented roles in collagen structural support, epidermal renewal, barrier integrity and the management of menopause-related symptom burden that affects skin quality.
The Compounding ApproachSuitable across your patient population without restrictions or exceptions.
Two contexts, one formulation
Balance is designed to support skin health from within as part of a patient’s daily routine through menopause and post-menopause — independent of any specific clinical treatment. For patients managing the visible consequences of oestrogen decline, including laxity, dryness, increased sensitivity and slower recovery, Balance provides a consistent internal foundation.
Suitable as a foundational daily nutraceutical for patients at any stage of the menopausal transition.
Treatments targeting menopausal skin changes — including collagen-stimulating laser, radiofrequency microneedling, dermal fillers and skin booster protocols — activate repair and remodelling processes that depend on adequate internal antioxidant and cofactor availability. Balance supports those resources across the full treatment cycle, from preparation through recovery and into ongoing maintenance.
Compatible with a broad range of professional skin treatments targeting volume loss and barrier compromise in menopausal patients.
Cellular renewal and collagen synthesis associated with visible skin ageing
Antioxidant activity, dermal hydration and skin clarity
Ready to order Balance for your clinic?
All formulations are compounded fresh to order and shipped directly to your clinic.