Psoriasis
Supporting the internal factors associated with psoriasis — immune regulation, healthy inflammatory response and skin barrier function.
The biological basis of psoriasis — and how internal support fits alongside treatment.
Psoriasis is influenced by both surface events and internal biological function. While topical and prescription treatments act primarily at the skin’s surface, psoriasis is driven by underlying biology — an immune-mediated inflammatory response that accelerates the growth and turnover of skin cells, producing the characteristic plaques and scale.
Dermatology literature describes psoriasis as a chronic, immune-mediated condition in which inflammatory signalling and rapid keratinocyte proliferation reinforce one another. Internal factors are increasingly discussed as part of the picture — immune and inflammatory balance, oxidative status, and micronutrient status relevant to skin function — together shaping the internal environment in which the skin regulates inflammation and cell turnover.
The Psoriasis formulation is designed to support the internal cofactors these processes depend on — providing a consistent internal foundation that sits alongside a patient’s topical or prescribed treatment, not in place of it.
What’s in the Psoriasis formulation — and why
This formulation represents the standard base composition for psoriasis-prone skin, designed for general clinical use and practitioner-led recommendation.
Each active is included at a defined dose for its documented role in a pathway relevant to psoriasis. Where evidence is limited or inconsistent, this is reflected in the wording — a key advantage of pharmacist compounding over standardised manufactured supplements.
| Ingredient | Primary pathway relevance | Mechanism | Evidence summary | Key reference |
|---|---|---|---|---|
| Vitamin A1000 IU | Epithelial differentiation | Supports normal keratinocyte differentiation and epithelial function | Supports normal epithelial differentiation and keratinocyte renewal. Provided at a nutritional dose — not equivalent to prescription retinoids | NIH Office of Dietary Supplements. Vitamin A Fact Sheet. |
| Vitamin E100 IU | Antioxidant defence | Lipid-soluble antioxidant protecting cell membranes from oxidative damage | Lipid-phase antioxidant protecting cell membranes from the oxidative stress associated with psoriatic inflammation | Ford AR et al. JAMA Dermatology. 2018;154(8):934–950 |
| Vitamin B12 (cyanocobalamin)0.25 mg | Normal cell metabolism | Supports DNA synthesis and normal cell division | Supports DNA synthesis and normal cell metabolism; included as a nutritional cofactor | NIH Office of Dietary Supplements. Vitamin B12 Fact Sheet. |
| Zinc picolinate50 mg (elemental zinc ~10 mg) | Immune & skin repair | Supports immune function, protein synthesis and normal repair | Zinc supports immune function, protein synthesis and normal wound repair, with relevance to barrier integrity | Dhaliwal S et al. American Journal of Clinical Dermatology. 2020;21(1):21–39 |
| Vitamin D3 (cholecalciferol)1000 IU | Immune regulation; keratinocyte biology | Influences immune signalling and keratinocyte growth | Vitamin D influences immune signalling and keratinocyte growth — both directly relevant to psoriasis biology | Dai Q et al. PLOS One. 2023;18(11):e0294239 |
| Palmitoylethanolamide (PEA)300 mg | Inflammatory signalling | Endogenous lipid mediator influencing mast-cell and inflammatory signalling | PEA modulates mast-cell activity and inflammatory signalling relevant to psoriatic inflammation | Petrosino S, Di Marzo V. British Journal of Pharmacology. 2017;174(11):1349–1365 |
References describe the pathway and supporting evidence relevant to each ingredient. This formulation supports the biological processes associated with psoriasis and is not intended to diagnose, treat, cure or prevent the condition.
Pharmaceutical-grade precision. Every ingredient has a purpose.
The Psoriasis formulation is compounded by licensed Australian pharmacists within established TGA regulatory frameworks, using pharmaceutical-grade raw materials selected for documented roles in immune regulation, inflammatory control and antioxidant defence.
The compounding approachTwo contexts, one formulation
The Psoriasis formulation is designed to support skin from within as part of a patient’s daily routine. For patients managing chronic plaques, it provides a consistent internal foundation targeting immune and inflammatory balance and the factors associated with skin cell turnover.
Topical, phototherapy and prescription psoriasis treatments act on the skin’s surface and local immune and proliferative processes. This formulation supports the internal resources — immune balance, inflammatory regulation and antioxidant status — that sit beneath those surface processes, complementing existing treatment rather than replacing it.
Ready to order the Psoriasis formulation for your clinic?
All formulations are compounded fresh to order and shipped directly to your clinic.